Delphinol® Superior ingredient for the maintenance of healthy bones
As the global demographics are changing rapidly, healthy ageing is becoming one of the major nutritional trends worldwide. By 2050, the number of people aged 60+ will have nearly doubled. People in this age group undoubtedly want to stay mobile and fit. However, men start to lose bone density at around 40 years of age, while the bone strength of women already decreases at around the age of 30 and rapidly declines due to hormonal changes in menopause.
Delphinol® showed significant effects on healthy bone metabolism in a pre-clinical study. The intake of Delphinol® increases bone mass by activating osteoblasts and inhibiting osteoclastogenesis, ultimately leading to the reconstitution of a balanced bone metabolism.
Unique Features
- Natural solution for the maintenance of normal bone structure
- Prevents bone loss and helps to build new bone
- Various product combinations feasible
Quality
Delphinol® is manufactured from selected fresh maqui berries under strict GMP conditions. The extract is standardised to bear a minimum of 25 % delphinidins and a minimum of 35 % total anthocyanins.
FIND OUT MORE ABOUT THE MAQUI BERRY
Delphinol® shows clinically proven bioavailability of key active ingredients.
| Market Applications | Details | References |
| Bone Health | A preclinical menopause osteoporosis model could demonstrate that, the oral administration of Delphinidin effectively prevented hormonal induced bone loss. | Moriwaki et al, 2014 |
| Bone Health | A preclinical menopause bone loss model demonstrated that the oral administration of Delphinol® effectively prevented hormonal induced loss in bone density. In addition it was shown that Delphinol® not only inhibited bone resorption, but also stimulated new bone formation. | Nagaoka et al, 2019 |
| Knochengesundheit | In an in vitro study with human osteoblasts, it was shown that Delphinol® protects bone cells from oxidative stress caused by cigarette smoke. Pre-treatment with Delphinol® was able to reverse the harmful effects of smoke-induced oxidative stress by blocking the generation of reactive oxygen species (ROS) and simultaneously enhancing the cells’ antioxidant defense system | Zhu et al., 2021 |
| Knochengesundheit | In an in vitro model using a 3D bone cell culture composed of osteoblasts and osteoclasts, the effects of Delphinol® on bone cells exposed to cigarette smoke extract were investigated. Delphinol® can significantly reduce the harmful effects caused by cigarette smoke on bone cells and thus help prevent smoke-induced disturbances in bone cell function and maintain balance in bone metabolism. | Guo et al., 2022 |
